CEACAM5 and colorectal carcinoma: Multivariate Cox regression analysis also showed that TM (HR = 2.226, p = 0.02), DD (HR = 4.376, p < 0.001), CA125 (HR = 3.851, p < 0.001), and CEA (HR = 5.929, p < 0.001) were independent prognostic variables for CRC patients.