Recent, studies39 on macrophages in NASH progression have identified NASH‐associated macrophages (NAMs), which notably possess a distinct array of molecular markers, including Gpnmb, Trem2, C1qa and Apoe, which were identified via our analysis of bulk RNA‐seq and validated by RT‐PCR (Figure 10F). Here, C1QA is linked to metabolic dysfunction-associated steatohepatitis.