In malignant glioma, CECR1 regulates PDGFB production in M2 TAMs, and TAM-derived PDGFB could promote PDGFRβ+ pericyte migration and secretion of VEGF-A and the proangiogenic ECM component periostin, thereby contributing to new vessel formation [138]. The gene discussed is PDGFB; the disease is malignant glioma.