The hepatic dysfunction associated with hyperthyroidism was attributed to improper exposure to high levels of thyroid hormones, hepatocyte anoxia and apoptosis resulting from excessive energy demand associated with hypermetabolic state provoking mitochondrial generation of the reactive oxygen species (ROS) as well as mitochondrial apoptotic pathway, hepatocytes degeneration subsequent to degradation of glycogen and protein in addition to hepatic necrosis following thyrotoxicosis cardiac failure [44, 45]. Here, TG is linked to hyperthyroidism.