CEACAM5 and neoplasm: In the multivariate Cox regression model, pT4 tumor stage (HR 2.58; 95% CI 1.06–6.25; P = 0.037) and elevated preoperative CEA (HR 2.93; 95% CI 1.26–6.82; P = 0.013) still were the independent prognostic factors of DFS, respectively.