The findings of this study have several clinical implications:Patients with comorbidities such as hypertension, a history of smoking, increased BMI, elevated hematocrit values, high Neutrophil-to-Lymphocyte Ratio (NLR), high Platelet-to-Lymphocyte Ratio (PLR), and increased C-reactive protein (CRP) levels are at a heightened risk for the development of Coronary Slow Flow (CSF). This evidence concerns the gene CRP and hypertensive disorder.