CLOCK and arthropathy: In SMR analysis of circadian clock genome-wide cis-mQTLs and outcomes (Supplementary Fig. 2, Supplementary Table 4), results found a total of 38 association signals across 32 unique genetic loci for UC, 37 association signals across 30 unique genetic loci for UC with PSC, and 29 association signals across 26 unique genetic loci for UC with arthropathy.