CRP and autoimmune disease: Our results showed that larger GA (OR 1.13,95%CI: 1.00-1.28, P = 0.042), PROM(≥ 18 h) (OR 2.39,95%CI: 1.35–4.23, P = 0.003) and maternal autoimmune diseases (OR 5.30,95%CI: 2.15–13.07, P < 0.001) had a significant association with CRP ≥ 8 mg/L, and these relationships were stable even when we adjusted for confounding factors in Table 2.