Genes related to inflammatory response (CXCL8, AQP9, INHBA, IL1B, CXCL6, and IL6) were upregulated in CD compared with non-IBD, while genes related to DNA repair (MPC2, VPS28, EDF1, ALYREF, and PCNA) and oxidative phosphorylation (IDH3B, ATP5MC1, ATP5ME, MRPL11, COX7C, and PHB2) were downregulated. The gene discussed is PHB2; the disease is inflammatory bowel disease.