ENO2 and ischemic stroke: As NSE has significant use in several neurological disorders, such as head injury, intracerebral hemorrhage, cardiac arrest, anoxic encephalopathy, encephalitis, and status epilepticus4, recent studies have investigated its relationship with ischemic stroke and its characteristics, such as infarcted brain volume, the severity of clinical manifestations, and short- and long-term prognosis9–12.