This further enhances HCC carcinogenesis through the Ras/Foxo4 signaling pathway.376 Moreover, SRSF10 promotes exon 6 exclusion in cell division cycle 25A (CDC25A) pre-mRNA, forming a stable CDC25A(△E6) isoform and producing a stronger cell cycle effect on HCC occurrence.377. Here, FOXO4 is linked to hepatocellular carcinoma.