PTBP1 and neoplasm: Besides, HNRNPA2B1 in HCC is regulated by miRNA, which inhibits NF-κB pathway activation by regulating HNRNPA2B1 ubiquitination, thereby inhibiting tumor metastasis.380 Shen et al. 381 obtained the expression level of PTBP1 in HCC tissues using the TCGA database and cell lines.