TP73α has a pro-tumor effect, while TP73β and TP73γ are associated with cancer suppression.211 Furthermore, SRSF3 regulates the PDGF-PDGFRB pathway and its downstream AKT and ERK abnormal activation by regulating TP73 AS as an intermediate hub, promoting GBM cell migration, proliferation, and angiogenesis.212. The gene discussed is TP73; the disease is neoplasm.