Research has shown that bone marrow mesenchymal stem cell-derived exosome (BMSC-Exo) reduced the expression of cyclin E1 (CCNE1) and CCNE2 through miR-144, thereby inhibiting the proliferation, colony formation, and S-phase arrest of NSCLC cells, preventing normal DNA synthesis and indirectly inhibiting tumour growth [108]. This evidence concerns the gene CCNE1 and non-small cell lung carcinoma.