In gastric cancer (GC), exosomal DACT3-AS1 derived from CAFs inhibited cell proliferation, migration, and invasion by targeting miR-181a-5p/sirtuin 1 (SIRT1) axis, and increased the sensitivity of GC cells to chemotherapy drugs through the SIRT1-mediated ferroptosis [102]. Here, SIRT1 is linked to gastric cancer.