FSTL3 and colorectal carcinoma: To elucidate the biological functions and mechanisms of FSTL3 in CRC development and immune evasion, lentivirus-mediated shFSTL3 and FSTL3Flag cDNA were delivered to HCT116 and HCT8 cells, so as to establish steady FSTL3-KD and FSTL3-OE cells.