In colocalisation analysis, pro-adrenomedullin and breast cancer risk (PPH4 = 94.4%), interleukin-23 receptor and pancreatic cancer risk (PPH4 = 73.9%), prothrombin and basal cell carcinoma risk (PPH4 = 81.8%), and interleukin-1 receptor-like 1 and triple-negative breast cancer risk (PPH4 = 85.6%) showed evidence of shared causal variants across traits. Here, IL1RL1 is linked to familial pancreatic carcinoma.