Again, in the same study, depression was not found to be substantially linked with the trajectory of CD4 T-cell reconstitution or the likelihood of immunologic failure (P value >0.05) but women with depression had increased incidence of oral thrush (HR: 1.15; 0.84–1.58; p = 0.38) and wasting (HR: 1.22; 95% CI: 0.81–1.83; p = 0.34) [33]. The gene discussed is CD4; the disease is major depressive disorder.