To identify the genomic regions where corin-induced histone posttranslational modification (PTM) changes take place in BRAFi-R melanoma cells following corin treatment, we performed ChIP-Seq for H3K27ac, H3K9ac, and H3K4me2 on chromatin extracts from BRAFi-R cells treated with DMSO or corin for 24 hours (Figure 7A). Here, CORIN is linked to melanoma.