In order to investigate mechanisms of corin resensitization of BRAFi-R melanoma cells to PLX4032, RNA-Seq was performed on 451Lu-R (MITFhi/AXLlo) and 1205Lu-R (MITFlo/AXLhi) cells treated with PLX4032 alone, corin alone, or corin in combination with PLX4032 for 24 hours. The gene discussed is CORIN; the disease is melanoma.