Indeed, T cells have been recently shown to selectively kill myofibroblasts through IFN-γ release and limit the progression of lung and liver fibrosis in preclinical models (Sobecki et al., 2022) and set up an immune memory in the long term since IFN-γ-producing tissue resident memory T cells protect against fibrosis progression (Collins et al., 2016), highlighting the importance IFN-γ-producing T cells in this disease. Here, IFNG is linked to Hepatic fibrosis.