We detected high activity of TNFα and NFκB signaling in monocytes, and high scores of the Interferon Gamma Response Hallmark signature in monocytes and tumor-associated monocyte-derived macrophages (Mo-Macs), while tissue-resident alveolar macrophages were characterized by high scores of the Oxidative Phosphorylation Hallmark signature. This evidence concerns the gene IFNG and neoplasm.