The hazard ratios of these genes are depicted in Fig. 1D, where apolipoprotein A5 (APOA5), Golgi SNAP receptor complex member 2 (GOSR2), regulator of G protein signaling 20 (RGS20), rabphilin 3A (RPH3A), transmembrane protein 167A (TMEM167A), t-complex 1 (TCP1), zinc finger DHHC-type palmitoyltransferase 15 (ZDHHC15), and ChaC glutathione specific gamma-glutamylcyclotransferase 1 (CHAC1) exhibited hazard ratios greater than 1, indicating an association with poorer survival outcomes in breast cancer patients with higher expression levels. This evidence concerns the gene CHAC1 and breast cancer.