Four miRNAs that were significantly negatively correlated with CCNB2 expression were all reduced in tumors (Fig. 6A), and their low expression was significantly associated with poor prognosis in ccRCC patients (Fig. 6B), suggesting that these miRNAs may have a diminished regulatory effect on CCNB2 expression in tumors resulting in a poor prognosis. Here, CCNB2 is linked to nonpapillary renal cell carcinoma.