PARD3 and cleft lip: Pathogenic variants in CHD3 show variable expressivity in Snijders Blok–Campeau syndrome (OMIM 618205), while PARD3 was associated before with neural tube defects, cleft lip, cleft palate, ASD, and bilateral adrenal hypoplasia (Chen et al. 2013; Cui et al. 2022; Özaslan et al. 2021; van der Spek et al. 2022).