Similar populations of expanded, cytotoxic Vδ1 T cell subsets with elevated expression of CD16, CD57 and NKG2C have been described in HCMV infection,20, 21, 22, 23 which is highly prevalent among PLWH (90–100% seropositivity).89, 90. The gene discussed is KLRC2; the disease is cytomegalovirus infection.