Our data highlight that, similar to both untreated HIV infection and EC cohorts, PLWH on ART exhibit the persistence of highly differentiated, TEMRA‐like Vδ1 T cells, and demonstrate that the phenotype of these highly differentiated Vδ1 T cells mirrors that of matured CD16+ NKG2C+ and CD16+ NKG2C+ CD57+ NK cell subsets. The gene discussed is B3GAT1; the disease is HIV infectious disease.