Overall, we found that proliferation (Figure 1) and IFNγ secretion (Supplementary Figure S1A) were both significantly increased in convalescent donors and that although the proliferative response was similar between PWUD and HD donors, PWUD showed a slight decrease in IFNγ secretion (Figure 1, Supplementary Figure S1A). The gene discussed is IFNG; the disease is Huntington disease.