ADAR and Alzheimer disease: Previous studies have reported widespread dysregulation of RNA editing efficiency of numerous RNAs in human AD as well as changes in the expression of ADAR1-3 that are collectively responsible for RNA editing (Akbarian et al., 1995; Gaisler-Salomon et al., 2014; Khermesh et al., 2016; Annese et al., 2018; Ma et al., 2021) and apparent mislocalisation of ADAR2 to the cytoplasm (Moore et al., 2019).