The mild inflammation associated to PM2.5 and PM10 exposure involves increased levels of biomarkers associated with cardiovascular diseases, such as C-reactive protein (CRP), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), LDH, propidium iodide, ROS, IL-8, peptidyl arginine deiminase 4 (PAD4), toll-like receptor 4 (TLR4) myeloperoxidase (MPO), and neutrophil elastase (NE) (Valderrama et al., 2022). This evidence concerns the gene TLR4 and cardiovascular disorder.