Homozygous microdeletion involving exon 5 of ZNF277 (NM_021994.2) (chr7:g111955948_111960100del, hg19) (n = 1) The microdeletion falls within the AUTS1 locus, a region linked to autistic spectrum disorders (ASDs). Moreover, ZNF277 is adjacent to the DOCK4 and IMMP2l genes, which have been implicated in ASD. (Deletion was heterozygous in parents (both with language problems in childhood. Deletion was absent in brother with mild language impairment.) The gene discussed is DOCK4; the disease is autism spectrum disorder.