GLUT4 has also been linked to Alzheimer’s disease, with several lines of research converging to suggest that the insulin-responsive glucose transporter GluT4 plays a key role in hippocampal memory processes, and that decreased activation of this transporter may underpin the cognitive impairment seen as a consequence of insulin resistance (McNay and Pearson-Leary, 2020). The gene discussed is INS; the disease is Alzheimer disease.