ACE and Hypertension: A previous study summarized the pharmacogenomics of hypertension treatment, and the most common genetic variants involved in the metabolism of the above five classes of drugs included ADRB1 (1165G > C), CYP2D6∗10, CYP2C9∗3, AGTR1 (1166A > C), ACE (I/D), CYP3A5∗3, and NPPA (2238T > C) [14].