To further understand the specific association of ADRB1 (CC vs. GC + GG) with stroke in different subpopulations, we conducted regression analysis by dividing the study subjects into different subgroups according to the presence of diabetes mellitus, presence of coronary heart disease, presence of COPD, presence of tumor, and whether they were taking BBs, ARBs, ACEIs, CCBs, and diuretics. This evidence concerns the gene ADRB1 and chronic obstructive pulmonary disease.