AGTR1 and hypertensive disorder: Another study conducted in Chinese Han hypertensive patients also found that CYP2D6∗10 was not in HWE [16]; this might be because CYP2D6∗10, AGTR1 (1166A > C), and NPPA (2238T > C) genes were associated with the development of hypertension [23, 35, 36].