A GWAS signal for AST and ALT colocalized with an eQTL for EFHD1, which codes for a mitochondrial protein known to regulate metabolic activity in B cells and neuronal cells41,42 A GWAS signal for LDL-C5 (Table S1) colocalized with an eQTL for LITAF, which is a BCL6 target gene that has been shown to enhance autophagy in B cell lymphomas.47 This evidence concerns the gene LITAF and B-cell non-Hodgkin lymphoma.