When stratified by sex, obesity, hs-CRP category, a statistically significant correlation was only observed in female (OR = 1.83; 95% CI, 1.20–2.79), those without obesity (OR = 2.07; 95% CI, 1.29–3.31), and those without hyper hs-CRP (OR = 2.11; 95% CI, 1.33–3.35). The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.