The patient carries two pathogenic somatic mutations among the endometrial tumors, MSH6 c.3261dupC (p.Phe1088LeufsTer5) and MSH2 c.445_448dup (p.Val150fs), in addition to a rare germline mutation MSH6 c.133G > C (p.Gly45Arg). Here, MSH2 is linked to endometrium neoplasm.