Second, we observed a significant upregulation of GAL3ST1 and FERT expression associated with the ectopic BORIS expression in BORIS-negative cell lines, HEK293T (human embryonic kidney) and MDA-MB-435 (melanoma cell line), respectively (Fig. 1d,e; Additional file 1: Fig. S1b-f). Here, GAL3ST1 is linked to melanoma.