To account for the heterogeneity of cancer cells and CAFs, we conducted single-cell RNA sequencing with CD45-negative enriched cells from surgical samples of 17 pancreatic tumor patients (16 pancreatic cancer and one HGD with IPMN pathology) (Fig. 1A). The gene discussed is PTPRC; the disease is pancreatic intraductal papillary-mucinous neoplasm.