Further, in addition to the circ_0114428/miR-574-5p/ROCK2 pathway, other regulatory pathways, such as circ_0001679/miR-338-3p/DUSP16 [36] and circPALM2/miR-330-5p/ROCK2 [37], also were involved in the occurrence of ALI, which suggested that the circ_0114428/miR-574-5p/ROCK2 axis was but one of the pathways related to ALI occurrence. This evidence concerns the gene DUSP16 and acute respiratory distress syndrome.