The odds of developing preeclampsia in patients with sFlt-1 /PlGF ratio > 38 was approximately 4-fold higher in COVID-19 group (OR = 4.71; 95% CI 1.16–19.13, p = 0.030) and 11-fold higher in controls (OR = 11.38; 95% CI 2.41–53.69, p = 0.002). Here, PGF is linked to COVID-19.