MSR1 and cancer: In addition, we tested whether the gain-of-function of CCL20 in the Cat D KO cancer cells, CD204+ TAM polarization, and Cox2 and Arg1 expression were rescued in TAMs primed by CCL20 overexpression in the Cat D KO cancer cells compared with those of TAMs primed by the Cat D KO cancer cells (Fig. 7i, j).