Overexpression of KCTD15 has been reported in several cancers, including breast cancer and leukaemia.6 Silencing of KCTD15 in cancer cell lines was antiproliferative and attenuated NF-κB signalling in models of KMT2A-rearranged leukaemia.7 8. This evidence concerns the gene KCTD15 and leukemia.