Combined, our above data argue that neither G3BP proteins nor G3BP1 complexes (SGs or RLBs) alter the activation of the RLR-MAVS-IRF3, OAS/RNase L, or PKR innate immune pathways in response to dsRNA lipofection or flavivirus infection, which contrasts with previous studies (18–24, 36). This evidence concerns the gene G3BP1 and Flavivirus Infections.