This hypothesis predicts that (i) preventing viral inhibition of G3BP function would increase viral RNA condensation, (ii) decreasing translation during viral infections would enhance viral RNA condensation, and (iii) decreasing the helicase function of the DEAD-box protein, eukaryotic initiation factor-4A (eIF4A), which limits the condensation of RNA by destabilizing short RNA duplexes (38), would also enhance viral RNA condensation. Here, G3BP1 is linked to viral infectious disease.