IFNB1 and COVID-19: The analyzed pathways show that the genes from mitochondria-, heart-, kidney-, and liver-related toxicity lists are closely related to COVID-19 and mitochondria, including the mitochondrial immune response to SARS-CoV-2, COVID-19 adverse outcome pathway, oxidative phosphorylation, type II interferon signaling, regulation of IFNA/IFNB signaling, and electron transport chain:OXPHOS system in mitochondria (Fig 6B).