In contrast, in clinical breast (n = 685 patients, SI Appendix, Fig. S1 C3) and pancreas (n = 310 patients, SI Appendix, Fig. S1 C4) carcinoma tissues, there are many long and curved CCTs with a high abundance of PMCA2 in the CCT membranes (SI Appendix, Fig. S1 C3 and C4). The gene discussed is ATP2B2; the disease is carcinoma.