When compared with the low Lp(a) and low-normal UACR group, both the low Lp(a) and high-normal UACR and high Lp(a) and high-normal UACR groups were significantly associated with increased risks of CKD, with HRs of 1.16 (95% CI 1.08-1.24; P<.001) and 1.32 (95% CI 1.19-1.46; P<.001), respectively. Here, LPA is linked to chronic kidney disease.