Table S2 in Multimedia Appendix 1 shows that a significant association between Lp(a) and increased CKD risk was only observed in the high-normal UACR group (HR 1.14, 95% CI 1.03-1.26; P=.01), but not in the low-normal UACR group (HR 0.98, 95% CI 0.90-1.08; P=.74). This evidence concerns the gene LPA and chronic kidney disease.