TET2 and chronic myelomonocytic leukemia: TET mutations are linked to diseases, inter aliahematopoietic malignancies such as chronic lymphocytic leukemia (CLL),acute myeloid leukemia (AML), and chronic myelomonocytic leukemia(CMML).28−30TET2 is among the most frequentlymutated genes in myeloid neoplasms and inactivating TET2 mutants are linked to DNA hypermethylation, tumor progression, andpoor patient outcome.