Furthermore, it has been demonstrated that Sox6 is a target gene of miRNA-499-5p (Li et al. 2013; Zhang et al. 2015; Wang et al. 2017), and recent studies have suggested that Sox6 may function as an EMT inhibitory factor in tumors, including breast cancer (Wang et al. 2018; Jiang et al. 2018). The gene discussed is SOX6; the disease is breast cancer.