ACVRL1 and pulmonary arterial hypertension: To delineate the transcriptomic signature of these cells, RNA-sequencing was performed, using the same experimental conditions described for ECFCs, i.e. using 3 CTLs and 2 ALK1-mutated HMVECs from PAH patients (MUT-P1 and -P2, Table 3) that were either stimulated overnight with BMP9 or BMP10 (10 ng/mL) or were left nonstimulated (NS).