This study lays the foundation for inferringthe functional mechanisms of PROSER2 and deciphering novel mechanismsfor the regulation of pancreatic cancer metastasis in the future.The study also underscores the possibility that uPE1 proteins playimportant roles in cancer progression that can potentially contributeto the development of diagnostic markers and targeted therapies forchallenging diseases. The gene discussed is PROSER2; the disease is familial pancreatic carcinoma.