Additionally, the decrease in the expressionof proteins, such as FAM20C, Dickkopf-1 (DKK1), prefoldin subunit1 (PFDN1), TYMS, and S100-calcium-binding protein 6 (S100A6), in PROSER2-overexpressingcells can potentially promote the epithelial–mesenchymal transitionin cancer. This evidence concerns the gene S100A6 and cancer.