Anxiety disorders have been associated with a specific cytokine patterns in rodents [49] and humans [45, 47, 50–52], characterized by an increased proinflammatory cytokines, such as IFN-γ [45, 47, 52], Tumor necrosis factor-alpha (TNF-α) [45, 49, 50], IL-6 [47, 50–52], IL-8 [47, 51], IL-1α [47], IL-2 [47], IL-1β [51], IL-12p70 [47], as well as reduced anti-inflammatory cytokines, including IL-10 [45]. Here, TNF is linked to anxiety disorder.