KCNA3 and amyotrophic lateral sclerosis: However, it would be interesting to test whether the effect of blockade of Kv1.3 in hSOD1G93A mice could also be relevant at later stages of the disease (e.g., 13 or 14 weeks of age), when very few drugs seem to have any effect on ALS mice, thus indicating a reliable treatment success in humans (Jiang et al., 2022).