CD274 and non-small cell lung carcinoma: We have demonstrated in our previous study that miRNA34acarriesthe potential to silence programmed cell death ligand 1 (PD-L1) genesin triple-negative breast cancer and non-small-cell lung cancer (NSCLC)after introducing inside the cells using a nonviral delivery vectorlike iron oxide nanorods (IONRs).21 Thisimmunotherapy approach using magnetic nanoparticles to deliver miRNA34aproved to be one of the efficient therapeutic approaches to kill cancercells.