The authors of a previous study reported a correlation between Toxoplasma antibodies (ATxA) in patients with autoimmune diseases and serum anti-centromere antibodies, such as anti-cardiolipin (CL), anti-beta2-glycoprotein-I (B2GPI), complex anti-cardiolipin-beta2-glycoprotein-I complex (anti-CL-B2) antibodies, anti-gliadin, anti-phosphatidylethanolamine (PE), anti-prothrombin (PT) and anti-scleroderma-70 (anti-Scl-70) [18]. Here, F2 is linked to autoimmune disease.