The data demonstrated, that only SNAI2 mRNA was affected, although differentially in the two cell lines, with a downregulation in the H23 lung carcinoma and upregulation in PANC-1 K-Ras(V12)/Akt2-kd clone A contribution of Akt in Slug/SNAI2 regulation is not without presence in the literature. The gene discussed is KRAS; the disease is lung carcinoma.